Do pragmatic trials trade-off internal validity for external validity?

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Do pragmatic trials trade-off internal validity for external validity?

Trials can be described as being on a design spectrum between highly explanatory (roughly, ‘Can the intervention work?’) to highly pragmatic (‘Does the intervention work in routine care?’). A criticism levelled at trials that take a pragmatic approach is that they sacrifice internal validity for external validity, i.e. there is a trade-off to be made. Proponents of pragmatic trials argue that t...

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BACKGROUND Controlled clinical trials of health care interventions are either explanatory or pragmatic. Explanatory trials test whether an intervention is efficacious; that is, whether it can have a beneficial effect in an ideal situation. Pragmatic trials measure effectiveness; they measure the degree of beneficial effect in real clinical practice. In pragmatic trials, a balance between extern...

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Debate Pragmatic controlled clinical trials in primary care : the struggle between external and internal validity

Background: Controlled clinical trials of health care interventions are either explanatory or pragmatic. Explanatory trials test whether an intervention is efficacious; that is, whether it can have a beneficial effect in an ideal situation. Pragmatic trials measure effectiveness; they measure the degree of beneficial effect in real clinical practice. In pragmatic trials, a balance between exter...

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Much of the methodological discussion around experiments in economics and other social sciences is framed in terms of the notions of internal and external validity. The standard view is that internal validity and external validity stand in a relationship best described as a trade-off. However, it is also commonly held that internal validity is a prerequisite to external validity. This article a...

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External, Internal and Construct Validity

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ژورنال

عنوان ژورنال: Trials

سال: 2015

ISSN: 1745-6215

DOI: 10.1186/1745-6215-16-s2-o81